In April 1966, Kerlan told Koufax it was time to retire

In April 1966, Kerlan told Koufax it was time to retire, that his arm could not take another season. Koufax kept Kerlan's advice to himself and went out every fourth day to pitch. He ended up pitching 323 innings and had a 27–9 record with a 1.73 ERA. Since then, no left-hander has had more wins, nor a lower ERA, in a season (Phillies pitcher Steve Carlton did match the 27-win mark in 1972). In the final game of the regular season, the Dodgers had to beat the Phillies to win the pennant. In the second game of a doubleheader, Koufax faced Jim Bunning for the second time that season,[60] in a match-up between perfect game winners. Koufax, on two days rest, pitched a complete game, 6–3 victory to clinch the pennant.[61] He started 41 games (for the second year in a row); only two left-handers started as many games in any season over the ensuing years through 2010.
The Dodgers went on to face the Baltimore Orioles in the 1966 World Series. Game 2 marked Koufax's third start in eight days. Koufax pitched well enough—Baltimore first baseman Boog Powell told Koufax's biographer, Jane Leavy, "He might have been hurtin' but he was bringin'"—but three errors by Dodger center fielder Willie Davis in the fifth inning produced three unearned runs. Baltimore's Jim Palmer pitched a four-hitter and the Dodgers ended up losing the game 6–0. Alston lifted Koufax at the end of the sixth inning with the idea of getting him extra rest before pitching a potential fifth Series game. It never happened; the Dodgers were swept in four, not scoring a single run in the last three. After the World Series, Koufax announced his retirement due to his arthritic condition.[62]


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